Saving Lives

The Saving Lives Podcast is a concise, evidence-based series focused on critical care medicine, hosted by Dr. Eddy Joe Gutierrez, a board-certified intensivist. Each episode delves into recent research and best practices pertinent to the management of critically ill patients.

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November 11, 2025

CCBs and Oxygenation: Why the Sat Falls After the Drip

Unexpected desaturation within an hour of starting intravenous nicardipine or clevidipine should prompt an immediate medication review. These infusions can blunt hypoxic pulmonary vasoconstriction, worsen ventilation–perfusion mismatch, and should be stopped before respiratory support is escalated.

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